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Table 6 Multivariate1 odds ratios (ORs) and 95% Confidence Intervals (CIs) for breast cancer by quintiles of absolute dense area and absolute non-dense area on a postmenopausal mammogram

From: Nondense mammographic area and risk of breast cancer

 

Quintiles non-dense area

 

1

OR (95% CI)

2

OR (95% CI)

3

OR (95% CI)

4

OR (95% CI)

5

OR (95% CI)

Quintiles dense area

     

1

2.92 (1.23-6.93)

1.39 (0.66-2.90)

1.73 (0.86-3.50)

1.04 (0.50-2.16)

1.00

cases/controls

16/29

26/80

35/85

24/83

16/56

2

3.75 (1.89-7.45)

1.98 (0.94-4.17)

1.58 (0.76-3.29)

2.05 (0.95-4.43)

1.42 (0.68-2.96)

cases/controls

65/91

27/62

27/74

23/43

25/62

3

3.68 (1.84-7.36)

1.84 (0.89-3.79)

1.58 (0.73-3.42)

2.05 (0.99-4.25)

1.73 (0.83-3.62)

cases/controls

59/82

31/77

21/56

30/62

26/56

4

4.82 (2.44-9.53)

3.30 (1.60-6.80)

3.01 (1.46-6.20)

2.91 (1.45-5.85)

1.80 (0.90-3.60)

cases/controls

80/76

41/53

37/55

44/65

38/83

5

4.29 (2.10-8.76)

3.83 (1.90-7.75)

4.36 (2.20-8.64)

2.88 (1.46-5.66)

2.15 (1.08-4.26)

cases/controls

51/55

52/60

66/63

57/79

43/75

  1. P interaction = 0.97
  2. 1) Adjusted for age at mammography (continuous), study (Nurses' Health Study, Nurses' Health Study II), age at menarche (< 12, 12-13, ≥ 14), family history of breast cancer (yes, no), parity + age at first birth (nulliparous, < 3 children age < 26, < 3 children age ≥ 26, ≥ 3 children age < 26, ≥ 3 children age ≥ 26), body mass index (< 20, 20-< 22.5, 22.5-< 25, 25-< 27.5, 27.5-< 30, 30-< 32.5, 32.5-< 35, ≥ 35 kg/m2), alcohol use (0, < 5, 5-< 15, ≥ 15 g/day, unknown), age at menopause (continuous), and current hormonal therapy (yes, no, unknown).
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Breast Cancer Research

ISSN: 1465-542X

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