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Table 6 Multivariate1 odds ratios (ORs) and 95% Confidence Intervals (CIs) for breast cancer by quintiles of absolute dense area and absolute non-dense area on a postmenopausal mammogram

From: Nondense mammographic area and risk of breast cancer

  Quintiles non-dense area
  1
OR (95% CI)
2
OR (95% CI)
3
OR (95% CI)
4
OR (95% CI)
5
OR (95% CI)
Quintiles dense area      
1 2.92 (1.23-6.93) 1.39 (0.66-2.90) 1.73 (0.86-3.50) 1.04 (0.50-2.16) 1.00
cases/controls 16/29 26/80 35/85 24/83 16/56
2 3.75 (1.89-7.45) 1.98 (0.94-4.17) 1.58 (0.76-3.29) 2.05 (0.95-4.43) 1.42 (0.68-2.96)
cases/controls 65/91 27/62 27/74 23/43 25/62
3 3.68 (1.84-7.36) 1.84 (0.89-3.79) 1.58 (0.73-3.42) 2.05 (0.99-4.25) 1.73 (0.83-3.62)
cases/controls 59/82 31/77 21/56 30/62 26/56
4 4.82 (2.44-9.53) 3.30 (1.60-6.80) 3.01 (1.46-6.20) 2.91 (1.45-5.85) 1.80 (0.90-3.60)
cases/controls 80/76 41/53 37/55 44/65 38/83
5 4.29 (2.10-8.76) 3.83 (1.90-7.75) 4.36 (2.20-8.64) 2.88 (1.46-5.66) 2.15 (1.08-4.26)
cases/controls 51/55 52/60 66/63 57/79 43/75
  1. P interaction = 0.97
  2. 1) Adjusted for age at mammography (continuous), study (Nurses' Health Study, Nurses' Health Study II), age at menarche (< 12, 12-13, ≥ 14), family history of breast cancer (yes, no), parity + age at first birth (nulliparous, < 3 children age < 26, < 3 children age ≥ 26, ≥ 3 children age < 26, ≥ 3 children age ≥ 26), body mass index (< 20, 20-< 22.5, 22.5-< 25, 25-< 27.5, 27.5-< 30, 30-< 32.5, 32.5-< 35, ≥ 35 kg/m2), alcohol use (0, < 5, 5-< 15, ≥ 15 g/day, unknown), age at menopause (continuous), and current hormonal therapy (yes, no, unknown).