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Table 5 Multivariate1 odds ratios (ORs) and 95% Confidence Intervals (CIs) for breast cancer by tertiles of absolute dense area and absolute non-dense area on a premenopausal mammogram

From: Nondense mammographic area and risk of breast cancer

  Tertiles non-dense area
  1
OR (95% CI)
2
OR (95% CI)
3
OR (95% CI)
Tertiles dense area    
1 2.40 (1.30-4.46) 2.13 (1.15-3.93) 1.00
cases/controls 51/122 38/91 24/117
2 3.44 (1.91-6.18) 2.28 (1.26-4.14) 1.76 (0.96-3.22)
cases/controls 76/131 46/111 34/97
3 5.10 (2.78-9.37) 3.16 (1.78-5.63) 2.78 (1.57-4.92)
cases/controls 65/77 69/137 61/115
  1. P interaction = 0.26
  2. 1) Adjusted for age at mammography (continuous), study (Nurses' Health Study, Nurses' Health Study II), age at menarche (< 12, 12-13, ≥ 14), family history of breast cancer (yes, no), parity + age at first birth (nulliparous, < 3 children age < 26, < 3 children age ≥ 26, ≥ 3 children age < 26, ≥ 3 children age ≥ 26), body mass index (< 20, 20-< 22.5, 22.5-< 25, 25-< 27.5, 27.5-< 30, 30-< 32.5, 32.5-< 35, ≥ 35 kg/m2), and alcohol use (0, < 5, 5-< 15, ≥ 15 g/day, unknown).