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Table 5 Multivariate1 odds ratios (ORs) and 95% Confidence Intervals (CIs) for breast cancer by tertiles of absolute dense area and absolute non-dense area on a premenopausal mammogram

From: Nondense mammographic area and risk of breast cancer

 

Tertiles non-dense area

 

1

OR (95% CI)

2

OR (95% CI)

3

OR (95% CI)

Tertiles dense area

   

1

2.40 (1.30-4.46)

2.13 (1.15-3.93)

1.00

cases/controls

51/122

38/91

24/117

2

3.44 (1.91-6.18)

2.28 (1.26-4.14)

1.76 (0.96-3.22)

cases/controls

76/131

46/111

34/97

3

5.10 (2.78-9.37)

3.16 (1.78-5.63)

2.78 (1.57-4.92)

cases/controls

65/77

69/137

61/115

  1. P interaction = 0.26
  2. 1) Adjusted for age at mammography (continuous), study (Nurses' Health Study, Nurses' Health Study II), age at menarche (< 12, 12-13, ≥ 14), family history of breast cancer (yes, no), parity + age at first birth (nulliparous, < 3 children age < 26, < 3 children age ≥ 26, ≥ 3 children age < 26, ≥ 3 children age ≥ 26), body mass index (< 20, 20-< 22.5, 22.5-< 25, 25-< 27.5, 27.5-< 30, 30-< 32.5, 32.5-< 35, ≥ 35 kg/m2), and alcohol use (0, < 5, 5-< 15, ≥ 15 g/day, unknown).
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Breast Cancer Research

ISSN: 1465-542X

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