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Table 3 Odds ratios for breast cancer according to tertiles of different premenopausal mammographic characteristics among 464 cases and 998 controls

From: Nondense mammographic area and risk of breast cancer

  Odds Ratios and 95% Confidence Intervals
Mammographic characteristics Cases Controls Model 11 Model 22 Model 33
Absolute dense area, tertiles         
1 113 330 1.00   1.00   1.00  
2 156 339 1.43 (1.07-1.92) 1.40 (1.04-1.88) 1.39 (1.03-1.87)
3 195 329 2.07 (1.52-2.84) 2.01 (1.45-2.77) 2.05 (1.48-2.84)
Absolute non-dense area, tertiles         
1 192 330 1.00   1.00   1.00  
2 153 339 0.77 (0.59-1.01) 0.72 (0.54-0.95) 0.69 (0.52-0.92)
3 119 329 0.62 (0.47-0.83) 0.51 (0.36-0.72) 0.50 (0.35-0.71)
Percent dense area, tertiles         
1 95 330 1.00   1.00   N/A  
2 167 339 1.75 (1.30-2.36) 1.95 (1.41-2.69)   
3 202 329 2.18 (1.62-2.92) 2.72 (1.93-3.83)   
  1. 1) Adjusted for age at mammography (continuous), study (Nurses' Health Study, Nurses' Health Study II).
  2. 2) Adjusted for age at mammography (continuous), study (Nurses' Health Study, Nurses' Health Study II), age at menarche (< 12, 12-13, ≥ 14), family history of breast cancer (yes, no), parity + age at first birth (nulliparous, < 3 children age < 26, < 3 children age ≥ 26, ≥ 3 children age < 26, ≥ 3 children age ≥ 26), body mass index (< 20, 20-< 22.5, 22.5-< 25, 25-< 27.5, 27.5-< 30, 30-< 32.5, 32.5-< 35, ≥ 35 kg/m2), and alcohol use (0, < 5, 5-< 15, ≥ 15 g/day, unknown).
  3. 3) Adjusted for covariates in model 2, plus absolute non-dense or absolute dense area (tertiles), as appropriate.