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Table 4 ORs and 95% CIs for combinations of ADRB2 and ADRB3 genetic polymorphisms

From: Possible association of β2- and β3-adrenergic receptor gene polymorphisms with susceptibility to breast cancer

Combined genotypes

     
  

Patients

Control

ORs for breast

Age-adjusted ORs

Mean BMI of control

ADRB2

ADRB3

(n)

individuals (n)

cancer (95% CI)

for breast cancer (95% CI)

individuals ± SD

Gln/Gln

Trp/Trp

119

98

1.00

1.00

22.3 ± 3.0

Gln/Gln

/Arg

56

52

0.89 (0.56-1.41)

0.88 (0.55-1.41)

22.1 ± 2.8

/Glu

Trp/Trp

21

23

0.75 (0.39-1.44)

0.76 (0.39-1.46)

22.4 ± 3.1

/Glu

/Arg

4

9

0.37 (0.11-1.23)

0.32 (0.10-1.10)

22.2 ± 2.9

  1. The total number of cases was 200, and that of control individuals was 182. /Arg, a combination of Trp/Arg and Arg/Arg; /Glu, a combination of Gln/Glu and Glu/Glu.