Table 3 ORs and 95% CIs for ADRB2 and ADRB3 genes
ADRB2 gene | ADRB3 gene | |||||
|---|---|---|---|---|---|---|
/Glu versus | /Glu versus | /Arg versus | /Arg versus | |||
Control | Gln/Gln | Gln/Gln OR (95% CI) | Trp/Trp | Trp/Trp OR (95% CI) | ||
Subjects | Patients | individuals | OR (95% CI) | adjusted for age | OR (95% CI) | adjusted for age |
All subjects | 200 | 182 | 0.67 (0.38-1.18) | 0.65 (0.37-1.16) | 0.85 (0.55-1.31) | 0.83 (0.54-1.29) |
Interval after diagnosis | ||||||
<3 years | 110 | 182 | 0.68 (0.35-1.35) | 0.67 (0.34-1.33) | 0.81 (0.49-1.36) | 0.80 (0.48-1.34) |
3-4 years | 90 | 182 | 0.65 (0.31-1.36) | 0.65 (0.31-1.38) | 0.90 (0.52-1.54) | 0.89 (0.51-1.55) |
Menopause | ||||||
Premenopausal | 109 | 95 | 0.72 (0.32-1.65) | 0.65 (0.28-1.51) | 0.75 (0.42-1.35) | 0.82 (0.45-1.48) |
Postmenopausal | 91 | 87 | 0.63 (0.29-1.38) | 0.58 (0.26-1.28) | 0.98 (0.51-1.87) | 0.93 (0.48-1.80) |
Body mass index | ||||||
<22 | 103 | 94 | 0.60 (0.27-1.33) | 0.54 (0.24-1.25) | 0.97 (0.53-1.77) | 0.92 (0.49-1.72) |
≥ 22 | 97 | 88 | 0.75 (0.34-1.69) | 0.76 (0.34-1.69) | 0.75 (0.40-1.38) | 0.74 (0.40-1.38) |
Menarche | ||||||
<14 years | 92 | 89 | 0.79 (0.34-1.88) | 0.78 (0.33-1.86) | 0.82 (0.44-1.53) | 0.83 (0.44-1.57) |
≥ 14 years* | 108 | 93 | 0.59 (0.28-1.25) | 0.54 (0.25-1.18) | 0.89 (0.49-1.62) | 0.81 (0.44-1.50) |
First birth | ||||||
<25 years | 84 | 67 | 0.35 (0.13-0.99) | 0.34 (0.12-0.97) | 0.92 (0.46-1.83) | 0.95 (0.47-1.93) |
≥ 25 years or no birth | 116 | 115 | 0.93 (0.47-1.85) | 0.93 (0.46-1.85) | 0.81 (0.46-1.41) | 0.78 (0.44-1.36) |
Family history of breast cancer, in mother or sister(s) | ||||||
No | 175 | 178 | 0.67 (0.37-1.23) | 0.65 (0.36-1.2) | 0.77 (0.49-1.20) | 0.75 (0.47-1.18) |
Yes | 25 | 4 | 0.19 (0.02-1.78) | 0.16 (0.01-1.78) | 2.36 (0.21-25.9) | 2.30 (0.20-26.6) |