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Table 3 ORs and 95% CIs for ADRB2 and ADRB3 genes

From: Possible association of β2- and β3-adrenergic receptor gene polymorphisms with susceptibility to breast cancer

    ADRB2 gene ADRB3 gene
    /Glu versus /Glu versus /Arg versus /Arg versus
   Control Gln/Gln Gln/Gln OR (95% CI) Trp/Trp Trp/Trp OR (95% CI)
Subjects Patients individuals OR (95% CI) adjusted for age OR (95% CI) adjusted for age
All subjects 200 182 0.67 (0.38-1.18) 0.65 (0.37-1.16) 0.85 (0.55-1.31) 0.83 (0.54-1.29)
Interval after diagnosis       
   <3 years 110 182 0.68 (0.35-1.35) 0.67 (0.34-1.33) 0.81 (0.49-1.36) 0.80 (0.48-1.34)
   3-4 years 90 182 0.65 (0.31-1.36) 0.65 (0.31-1.38) 0.90 (0.52-1.54) 0.89 (0.51-1.55)
Menopause       
   Premenopausal 109 95 0.72 (0.32-1.65) 0.65 (0.28-1.51) 0.75 (0.42-1.35) 0.82 (0.45-1.48)
   Postmenopausal 91 87 0.63 (0.29-1.38) 0.58 (0.26-1.28) 0.98 (0.51-1.87) 0.93 (0.48-1.80)
Body mass index       
   <22 103 94 0.60 (0.27-1.33) 0.54 (0.24-1.25) 0.97 (0.53-1.77) 0.92 (0.49-1.72)
   ≥ 22 97 88 0.75 (0.34-1.69) 0.76 (0.34-1.69) 0.75 (0.40-1.38) 0.74 (0.40-1.38)
Menarche       
   <14 years 92 89 0.79 (0.34-1.88) 0.78 (0.33-1.86) 0.82 (0.44-1.53) 0.83 (0.44-1.57)
   ≥ 14 years* 108 93 0.59 (0.28-1.25) 0.54 (0.25-1.18) 0.89 (0.49-1.62) 0.81 (0.44-1.50)
First birth       
   <25 years 84 67 0.35 (0.13-0.99) 0.34 (0.12-0.97) 0.92 (0.46-1.83) 0.95 (0.47-1.93)
   ≥ 25 years or no birth 116 115 0.93 (0.47-1.85) 0.93 (0.46-1.85) 0.81 (0.46-1.41) 0.78 (0.44-1.36)
Family history of breast cancer, in mother or sister(s)
   No 175 178 0.67 (0.37-1.23) 0.65 (0.36-1.2) 0.77 (0.49-1.20) 0.75 (0.47-1.18)
   Yes 25 4 0.19 (0.02-1.78) 0.16 (0.01-1.78) 2.36 (0.21-25.9) 2.30 (0.20-26.6)
  1. *One missing value in the case group. /Arg, a combination of Trp/Arg and Arg/Arg; /Glu, a combination of Gln/Glu and Glu/Glu.