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Table 4 Effects of nomegestrol alone or in combination with adriamycin on cell cycle in MCF7/ADR cells

From: Reversal effects of nomegestrol acetate on multidrug resistance in adriamycin-resistant MCF7 breast cancer cell line

 

ADR alone

ADR+ NOM (20 μM)

ADR concentration (μM)

G0G1

S

G2/M

G0G1

S

G2/M

0 (control)

40

60

0

47

52.8

0.2

5

40

60

0

52

47.8

0.2

10

39

60

1

38

55.6

6.4

20

52

46

2

30

46

24

40

50

45

5

3

66.6

30.4

  1. Values are percentages of cells at the indicated cell cycle stages. ADR, adriamycin; NOM, nomegestrol.