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Figure 4 | Breast Cancer Research

Figure 4

From: Genomic and phenotypic analysis of BRCA2mutated breast cancers reveals co-occurring changes linked to progression

Figure 4

Two-class comparative analysis displaying event-frequency plots for BRCA2 tumors with (blue) and without (red) evidence for lymph node metastases at diagnosis. The fraction of tumors with acquired changes are represented on the y-axis with positive values for gains, and negative for deletions, ordered by chromosomal location on x-axis from p- to q-arm, from left to right. The significance scores (d), derived from a permutation-based procedure (SAM two-class unpaired), representing the strength of association, are shown in the lower panel with relations below a false-discovery rate of 0.05 indicated in red (cytoband locations).

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