Skip to main content

Table 1 Intensity and distribution of CX3CR1 in normal and malignant breast tissues

From: The chemokine receptor CX3CR1 is directly involved in the arrest of breast cancer cells to the skeleton

Tissues 0 0 to 1 1 to 2 2 to 3 Total
Normal 21 (45%) 19 (40%) 6 (13%) 1 (2%) 47
Malignant 43 (21%) 54 (27%) 53 (26%) 52 (26%) 202
  1. Staining intensity was scored based on a scale in which negative specimens were graded (0) and strongly positive samples were graded (3). To evaluate distribution, tissues with complete lack of staining were scored as (0); tissues prevalently negative for CX3CR1 displaying some areas of positive staining were scored as (0 to 1); tissues showing uniform staining for CX3CR1 were scored as either (1 to 2) or (2 to 3), based on the intensity of the signal observed. The increase in CX3CR1 expression observed in cancer samples as compared to normal samples resulted to be statistically significant with a P-value equal to 0.0016.