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Table 2 Differentially expressed genes on regions with differential copy number

From: Breast tumors from CHEK2 1100delC- mutation carriers: genomic landscape and clinical implications

Gene symbol GEX: fold change GEX: P value Region aCGH: gain/loss
CLCA1 1.8178 0.000007 chr1 Loss
DPH5 0.8254 0.0049 chr1 Loss
C1orf62 1.3277 0.0057 chr1 Loss
ATXN7L2 1.2804 0.007 chr1 Loss
DR1 0.8474 0.0108 chr1 Loss
TMED5 0.8728 0.0145 chr1 Loss
ALG14 0.8640 0.0389 chr1 Loss
LRRC8D 0.8854 0.0433 chr1 Loss
DEFA5 1.1076 0.0113 chr8 Loss
DUSP4 1.2724 0.0426 chr8 Loss
OR6C3 1.2558 0.0016 chr12 Gain
CALCOCO1 1.2579 0.0016 chr12 Gain
SBEM 3.0936 0.0217 chr12 Gain
OR6C2 1.1820 0.0485 chr12 Gain
LRP1 0.8171 0.0011 chr12 Gain
OR10AD1 1.2648 0.0061 chr12 Gain
CSAD 1.2758 0.0067 chr12 Gain
C12orf10 0.8867 0.0122 chr12 Gain
MYO1A 0.7468 0.0131 chr12 Gain
LALBA 1.2369 0.0187 chr12 Gain
ITGA7 1.2531 0.0201 chr12 Gain
OR9K2 1.4794 0.0231 chr12 Gain
KRT5 1.7237 0.0382 chr12 Gain
FAM112B 0.7840 0.0426 chr12 Gain
SMARCC2 1.1788 0.047 chr12 Gain
KIAA1924 0.8549 0.0156 chr16 Gain
NTHL1 0.8410 0.0233 chr16 Gain
KIAA1171 1.1890 0.0348 chr16 Gain
  1. Five of eight differentially expressed genes on 1p13.3-31.3 show reduced expression levels. On 12q13.11-3, 11 of 15 genes show elevated expression. aCGH, array comparative genomic hybridization; GEX, gene expression.