From: Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK
Mouse line
Tumor incidence
Mean age of tumor bearing mice (days)
Mean parity of tumor bearing mice
Wild Type
0.095 (2/21)
608 (552, 665)
3 litters (3)
Brk83
0.300 (6/20)
316 (range: 150 to 453)
1.5 litters (range: 0 to 4)