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Table 4 Breast tumor ER, PgR, HER2 and EGFR expression and the bone, the liver and the lungs as the first sites of distant recurrence

From: Breast cancer biological subtypes and protein expression predict for the preferential distant metastasis sites: a nationwide cohort study

Primary tumor protein expression

First distant site of breast cancer recurrence

 

Bone

Liver

Lung

 

N = 102 n (%)

N = 48 n (%)

N = 33 n (%)

ER +

64 (62.7)

25 (52.1)

15 (45.5)

PgR +

46 (45.1)

18 (37.5)

9 (27.3)

ER + and/or PgR +

69 (67.6)

26 (54.2)

15 (45.5)

HER2 +

26 (25.5)

16 (33.3)

16 (48.5)

EGFR + (HER1)

16 (15.7)

11 (22.9)

15 (45.5)

EGFR + and/or HER2 +

37 (36.3)

20 (41.7)

25 (75.8)

  1. EGFR, epidermal growth factor receptor; ER, estrogen receptor, HER1, human epidermal growth factor receptor-1; HER2, human epidermal growth factor receptor-2; PgR, progesterone receptor.