Table 2 Breast cancer molecular subtype and the first site of distant metastases
First distant site of breast cancer recurrence | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Breast cancer molecular subtype | No. of patients1 | No. of metastatic sites | Bone | Liver | Lung | Non-regional lymph nodes | Skin | Pleura | Brain | Other |
n | n | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |
Luminal A | 123 | 164 | 77 (47.0) | 29 (17.7) | 14 (8.5) | 10 (6.1) | 12 (7.3) | 9 (5.6) | 3 (1.8) | 10 (6.1) |
Luminal B | 30 | 43 | 15 (34.9) | 5 (11.6) | 7 (16.3) | 5 (11.6) | 5 (11.6) | 3 (7.0) | 0 (0.0) | 3 (2.3) |
HER2+/HR- | 36 | 48 | 14 (29.2) | 13 (27.1) | 11 (22.9) | 4 (8.3) | 4 (8.3) | 0 (0.0) | 1 (2.1) | 1 (2.1) |
Basal-like | 26 | 42 | 12 (28.6) | 4 (9.5) | 10 (20.8) | 5 (11.9) | 3 (7.1) | 3 (7.1) | 4 (9.5) | 1 (2.4) |
Non-expressor | 19 | 24 | 9 (37.5) | 6 (25.0) | 0 (8.3) | 2 (8.3) | 0 (0.0) | 3 (12.5) | 3 (12.5) | 1 (4.2) |
Total | 234 | 321 | 127 (39.6) | 57 (17.8) | 42 (13.1) | 26 (8.1) | 24 (7.5) | 18 (5.6) | 11 (3.4) | 16 (5.0) |