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Table 7 ER+/PR+ subgroup-specific differences in serum U6, 5S, and other RNAs

From: Persistent upregulation of U6:SNORD44 small RNA ratio in the serum of breast cancer patients

Column ID Pvalue Fold change
Metastasis versus healthy
   U6 0.0024 3.26
   U6-SNORD44 0.003 4.18
   miR-16 0.001 2.83
   miR-16-SNORD44 0.002 3.65
   5S 0.0027 -21
   5S-SNORD44 0.007 -16
   SNORD44 0.275 -1.3
Cancer-free versus healthy
   U6 3.09 × 10-5 5.4
   U6-SNORD44 0.0002 6.35
   miR-16 0.004 2.46
   miR-16-SNORD44 0.01 2.9
   5S 0.05 -7.2
   5S-SNORD44 0.07 -6.16
   SNORD44 0.51 -1.17
Metastasis versus cancer-free
   U6 0.16 -1.68
   U6-SNORD44 0.37 -1.51
   miR-16 0.64 1.14
   miR-16-SNORD44 0.55 1.27
   5S 0.268 -2.93
   5S-SNORD44 0.326 -2.65
   SNORD44 0.66 -1.11
  1. Sera of patients with estrogen receptor/progesterone receptor-positive (ER/PR+) breast cancer were compared with those of healthy subjects (cohort 2). miR-16, microRNA 16; SNORD44, small nucleolar RNA 44.