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Table 6 Comparison of expression levels of U6, 5S, and other RNAs in the serum

From: Persistent upregulation of U6:SNORD44 small RNA ratio in the serum of breast cancer patients

Column ID

Pvalue

Fold change

Metastasis versus healthy

   U6

0.0005

4.31

   U6-SNORD44

0.004

4.8

   miR-16

0.001

3.4

   miR-16-SNORD44

0.008

3.7

   5S

0.0058

-23

   5S-SNORD44

0.009

-21

   SNORD44

0.708

-1.1

Cancer-free versus healthy

   U6

3.68 × 10-5

5.35

   U6-SNORD44

0.00028

6.64

   miR-16

0.0095

2.45

   miR-16-SNORD44

0.015

3.04

   5S

0.02

-11.0

   5S-SNORD44

0.037

-9.0

   SNORD44

0.39

-1.24

Metastasis versus cancer-free

   U6

0.59

-1.24

   U6-SNORD44

0.53

-1.39

   miR-16

0.38

1.37

   miR-16-SNORD44

0.67

1.23

   5S

0.51

-2.06

   5S-SNORD44

0.46

-2.38

   SNORD44

0.68

1.12

  1. Comparisons were made between healthy subjects and patients with metastasis, healthy subjects and cancer-free patients, and patients with metastasis and those who were cancer-free (cohort 2). miR-16, microRNA 16; SNORD44, small nucleolar RNA 44.