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Table 4 Differences in the levels of U6, 5S, and other RNAs between healthy subjects and patients with cancer

From: Persistent upregulation of U6:SNORD44 small RNA ratio in the serum of breast cancer patients

Small RNA

Pvalue

Fold change (cancer/healthy)

U6

0.001

2.42

5S

0.017

1.7

miR-21

0.72

-1.04

miR-16

0.72

-1.06

SNORD44

0.147

1.08

U6-miR-16

0.0047

2.58

U6-SNORD44

0.0028

2.22

5S-miR-16

0.02

1.82

5S-SNORD44

0.0599

1.53

miR-21-miR-16

0.93

1.01

miR-21-SNORD44

0.36

-1.14

  1. In this experimental cohort, patients were cancer-free at the time of serum collection. miR-16, microRNA 16; miR-21, microRNA 21; SNORD44, small nucleolar RNA 44.