TY - JOUR AU - Mantovani, A. AU - Allavena, P. AU - Sica, A. AU - Balkwill, F. PY - 2008 DA - 2008// TI - Cancer-related inflammation JO - Nature VL - 454 UR - https://doi.org/10.1038/nature07205 DO - 10.1038/nature07205 ID - Mantovani2008 ER - TY - JOUR AU - Mantovani, A. PY - 2010 DA - 2010// TI - Molecular pathways linking inflammation and cancer JO - Curr Mol Med VL - 10 UR - https://doi.org/10.2174/156652410791316968 DO - 10.2174/156652410791316968 ID - Mantovani2010 ER - TY - JOUR AU - Ghosh, S. AU - May, M. J. AU - Kopp, E. B. PY - 1998 DA - 1998// TI - NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses JO - Annu Rev Immunol VL - 16 UR - https://doi.org/10.1146/annurev.immunol.16.1.225 DO - 10.1146/annurev.immunol.16.1.225 ID - Ghosh1998 ER - TY - JOUR AU - Vallabhapurapu, S. AU - Karin, M. PY - 2009 DA - 2009// TI - Regulation and function of NF-kappaB transcription factors in the immune system JO - Annu Rev Immunol VL - 27 UR - https://doi.org/10.1146/annurev.immunol.021908.132641 DO - 10.1146/annurev.immunol.021908.132641 ID - Vallabhapurapu2009 ER - TY - JOUR AU - Baeuerle, P. A. AU - Baltimore, D. PY - 1988 DA - 1988// TI - I kappa B: a specific inhibitor of the NF-kappa B transcription factor JO - Science VL - 242 UR - https://doi.org/10.1126/science.3140380 DO - 10.1126/science.3140380 ID - Baeuerle1988 ER - TY - JOUR AU - Hayden, M. S. AU - Ghosh, S. PY - 2008 DA - 2008// TI - Shared principles in NF-kappaB signaling JO - Cell VL - 132 UR - https://doi.org/10.1016/j.cell.2008.01.020 DO - 10.1016/j.cell.2008.01.020 ID - Hayden2008 ER - TY - JOUR AU - Baldwin, A. S. PY - 1996 DA - 1996// TI - The NF-kappa B and I kappa B proteins: new discoveries and insights JO - Annu Rev Immunol VL - 14 UR - https://doi.org/10.1146/annurev.immunol.14.1.649 DO - 10.1146/annurev.immunol.14.1.649 ID - Baldwin1996 ER - TY - JOUR AU - Cheng, D. S. AU - Han, W. AU - Chen, S. M. AU - Sherrill, T. P. AU - Chont, M. AU - Park, G. Y. AU - Sheller, J. R. AU - Polosukhin, V. V. AU - Christman, J. W. AU - Yull, F. E. AU - Blackwell, T. S. PY - 2007 DA - 2007// TI - Airway epithelium controls lung inflammation and injury through the NF-kappa B pathway JO - J Immunol VL - 178 UR - https://doi.org/10.4049/jimmunol.178.10.6504 DO - 10.4049/jimmunol.178.10.6504 ID - Cheng2007 ER - TY - JOUR AU - Connelly, L. AU - Barham, W. AU - Onishko, H. M. AU - Sherrill, T. AU - Chodosh, L. A. AU - Blackwell, T. S. AU - Yull, F. E. PY - 2011 DA - 2011// TI - Inhibition of NF-kappaB activity in mammary epithelium increases tumor latency and decreases tumor burden JO - Oncogene VL - 30 UR - https://doi.org/10.1038/onc.2010.521 DO - 10.1038/onc.2010.521 ID - Connelly2011 ER - TY - JOUR AU - Connelly, L. AU - Barham, W. AU - Pigg, R. AU - Saint-Jean, L. AU - Sherrill, T. AU - Cheng, D. S. AU - Chodosh, L. A. AU - Blackwell, T. S. AU - Yull, F. E. PY - 2010 DA - 2010// TI - Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection JO - J Cell Physiol VL - 222 UR - https://doi.org/10.1002/jcp.21922 DO - 10.1002/jcp.21922 ID - Connelly2010 ER - TY - JOUR AU - Pollard, J. W. PY - 2004 DA - 2004// TI - Tumour-educated macrophages promote tumour progression and metastasis JO - Nat Rev Cancer VL - 4 UR - https://doi.org/10.1038/nrc1256 DO - 10.1038/nrc1256 ID - Pollard2004 ER - TY - JOUR AU - Coffelt, S. B. AU - Hughes, R. AU - Lewis, C. E. PY - 2009 DA - 2009// TI - Tumor-associated macrophages: effectors of angiogenesis and tumor progression JO - Biochim Biophys Acta VL - 1796 ID - Coffelt2009 ER - TY - JOUR AU - Lewis, C. E. AU - Pollard, J. W. PY - 2006 DA - 2006// TI - Distinct role of macrophages in different tumor microenvironments JO - Cancer Res VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-05-4005 DO - 10.1158/0008-5472.CAN-05-4005 ID - Lewis2006 ER - TY - JOUR AU - Biswas, S. K. AU - Sica, A. AU - Lewis, C. E. PY - 2008 DA - 2008// TI - Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms JO - J Immunol VL - 180 UR - https://doi.org/10.4049/jimmunol.180.4.2011 DO - 10.4049/jimmunol.180.4.2011 ID - Biswas2008 ER - TY - JOUR AU - Allavena, P. AU - Sica, A. AU - Solinas, G. AU - Porta, C. AU - Mantovani, A. PY - 2008 DA - 2008// TI - The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages JO - Crit Rev Oncol Hematol VL - 66 UR - https://doi.org/10.1016/j.critrevonc.2007.07.004 DO - 10.1016/j.critrevonc.2007.07.004 ID - Allavena2008 ER - TY - JOUR AU - Biswas, S. K. AU - Gangi, L. AU - Paul, S. AU - Schioppa, T. AU - Saccani, A. AU - Sironi, M. AU - Bottazzi, B. AU - Doni, A. AU - Vincenzo, B. AU - Pasqualini, F. AU - Vago, L. AU - Nebuloni, M. AU - Mantovani, A. AU - Sica, A. PY - 2006 DA - 2006// TI - A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation) JO - Blood VL - 107 UR - https://doi.org/10.1182/blood-2005-01-0428 DO - 10.1182/blood-2005-01-0428 ID - Biswas2006 ER - TY - JOUR AU - Greten, F. R. AU - Eckmann, L. AU - Greten, T. F. AU - Park, J. M. AU - Li, Z. W. AU - Egan, L. J. AU - Kagnoff, M. F. AU - Karin, M. PY - 2004 DA - 2004// TI - IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer JO - Cell VL - 118 UR - https://doi.org/10.1016/j.cell.2004.07.013 DO - 10.1016/j.cell.2004.07.013 ID - Greten2004 ER - TY - JOUR AU - Maeda, S. AU - Kamata, H. AU - Luo, J. L. AU - Leffert, H. AU - Karin, M. PY - 2005 DA - 2005// TI - IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis JO - Cell VL - 121 UR - https://doi.org/10.1016/j.cell.2005.04.014 DO - 10.1016/j.cell.2005.04.014 ID - Maeda2005 ER - TY - JOUR AU - Hagemann, T. AU - Wilson, J. AU - Burke, F. AU - Kulbe, H. AU - Li, N. F. AU - Pluddemann, A. AU - Charles, K. AU - Gordon, S. AU - Balkwill, F. R. PY - 2006 DA - 2006// TI - Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype JO - J Immunol VL - 176 UR - https://doi.org/10.4049/jimmunol.176.8.5023 DO - 10.4049/jimmunol.176.8.5023 ID - Hagemann2006 ER - TY - JOUR AU - Hagemann, T. AU - Wilson, J. AU - Kulbe, H. AU - Li, N. F. AU - Leinster, D. A. AU - Charles, K. AU - Klemm, F. AU - Pukrop, T. AU - Binder, C. AU - Balkwill, F. R. PY - 2005 DA - 2005// TI - Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK JO - J Immunol VL - 175 UR - https://doi.org/10.4049/jimmunol.175.2.1197 DO - 10.4049/jimmunol.175.2.1197 ID - Hagemann2005 ER - TY - JOUR AU - Hagemann, T. AU - Lawrence, T. AU - McNeish, I. AU - Charles, K. A. AU - Kulbe, H. AU - Thompson, R. G. AU - Robinson, S. C. AU - Balkwill, F. R. PY - 2008 DA - 2008// TI - "Re-educating" tumor-associated macrophages by targeting NF-kappaB JO - J Exp Med VL - 205 UR - https://doi.org/10.1084/jem.20080108 DO - 10.1084/jem.20080108 ID - Hagemann2008 ER - TY - JOUR AU - Martin, M. D. AU - Fingleton, B. AU - Lynch, C. C. AU - Wells, S. AU - McIntyre, J. O. AU - Piston, D. W. AU - Matrisian, L. M. PY - 2008 DA - 2008// TI - Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth JO - Clin Exp Metastasis VL - 25 UR - https://doi.org/10.1007/s10585-008-9206-y DO - 10.1007/s10585-008-9206-y ID - Martin2008 ER - TY - JOUR AU - Sasmono, R. T. AU - Oceandy, D. AU - Pollard, J. W. AU - Tong, W. AU - Pavli, P. AU - Wainwright, B. J. AU - Ostrowski, M. C. AU - Himes, S. R. AU - Hume, D. A. PY - 2003 DA - 2003// TI - A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse JO - Blood VL - 101 UR - https://doi.org/10.1182/blood-2002-02-0569 DO - 10.1182/blood-2002-02-0569 ID - Sasmono2003 ER - TY - JOUR AU - Soriano, P. PY - 1999 DA - 1999// TI - Generalized lacZ expression with the ROSA26 Cre reporter strain JO - Nat Genet VL - 21 UR - https://doi.org/10.1038/5007 DO - 10.1038/5007 ID - Soriano1999 ER - TY - JOUR AU - Muzumdar, M. D. AU - Tasic, B. AU - Miyamichi, K. AU - Li, L. AU - Luo, L. PY - 2007 DA - 2007// TI - A global double-fluorescent Cre reporter mouse JO - Genesis VL - 45 UR - https://doi.org/10.1002/dvg.20335 DO - 10.1002/dvg.20335 ID - Muzumdar2007 ER - TY - JOUR AU - Perl, A. K. AU - Wert, S. E. AU - Nagy, A. AU - Lobe, C. G. AU - Whitsett, J. A. PY - 2002 DA - 2002// TI - Early restriction of peripheral and proximal cell lineages during formation of the lung JO - Proc Natl Acad Sci USA VL - 99 UR - https://doi.org/10.1073/pnas.152238499 DO - 10.1073/pnas.152238499 ID - Perl2002 ER - TY - JOUR AU - Yee, K. O. AU - Connolly, C. M. AU - Duquette, M. AU - Kazerounian, S. AU - Washington, R. AU - Lawler, J. PY - 2009 DA - 2009// TI - The effect of thrombospondin-1 on breast cancer metastasis JO - Breast Cancer Res Treat VL - 114 UR - https://doi.org/10.1007/s10549-008-9992-6 DO - 10.1007/s10549-008-9992-6 ID - Yee2009 ER - TY - JOUR AU - Connelly, L. AU - Jacobs, A. T. AU - Palacios-Callender, M. AU - Moncada, S. AU - Hobbs, A. J. PY - 2003 DA - 2003// TI - Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression JO - J Biol Chem VL - 278 UR - https://doi.org/10.1074/jbc.M302238200 DO - 10.1074/jbc.M302238200 ID - Connelly2003 ER - TY - JOUR AU - Kusmartsev, S. AU - Gabrilovich, D. I. PY - 2006 DA - 2006// TI - Effect of tumor-derived cytokines and growth factors on differentiation and immune suppressive features of myeloid cells in cancer JO - Cancer Metastasis Rev VL - 25 UR - https://doi.org/10.1007/s10555-006-9002-6 DO - 10.1007/s10555-006-9002-6 ID - Kusmartsev2006 ER - TY - JOUR AU - Ostrand-Rosenberg, S. AU - Sinha, P. PY - 2009 DA - 2009// TI - Myeloid-derived suppressor cells: linking inflammation and cancer JO - J Immunol VL - 182 UR - https://doi.org/10.4049/jimmunol.0802740 DO - 10.4049/jimmunol.0802740 ID - Ostrand-Rosenberg2009 ER - TY - JOUR AU - Mosser, D. M. AU - Edwards, J. P. PY - 2008 DA - 2008// TI - Exploring the full spectrum of macrophage activation JO - Nat Rev Immunol VL - 8 UR - https://doi.org/10.1038/nri2448 DO - 10.1038/nri2448 ID - Mosser2008 ER - TY - JOUR AU - Gonzalez-Juarrero, M. AU - Shim, T. S. AU - Kipnis, A. AU - Junqueira-Kipnis, A. P. AU - Orme, I. M. PY - 2003 DA - 2003// TI - Dynamics of macrophage cell populations during murine pulmonary tuberculosis JO - J Immunol VL - 171 UR - https://doi.org/10.4049/jimmunol.171.6.3128 DO - 10.4049/jimmunol.171.6.3128 ID - Gonzalez-Juarrero2003 ER - TY - JOUR AU - Benoit, M. AU - Desnues, B. AU - Mege, J. L. PY - 2008 DA - 2008// TI - Macrophage polarization in bacterial infections JO - J Immunol VL - 181 UR - https://doi.org/10.4049/jimmunol.181.6.3733 DO - 10.4049/jimmunol.181.6.3733 ID - Benoit2008 ER - TY - JOUR AU - Walser, T. C. AU - Ma, X. AU - Kundu, N. AU - Dorsey, R. AU - Goloubeva, O. AU - Fulton, A. M. PY - 2007 DA - 2007// TI - Immune-mediated modulation of breast cancer growth and metastasis by the chemokine Mig (CXCL9) in a murine model JO - J Immunother VL - 30 UR - https://doi.org/10.1097/CJI.0b013e318031b551 DO - 10.1097/CJI.0b013e318031b551 ID - Walser2007 ER - TY - JOUR AU - Saccani, A. AU - Schioppa, T. AU - Porta, C. AU - Biswas, S. K. AU - Nebuloni, M. AU - Vago, L. AU - Bottazzi, B. AU - Colombo, M. P. AU - Mantovani, A. AU - Sica, A. PY - 2006 DA - 2006// TI - p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance JO - Cancer Res VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-06-1867 DO - 10.1158/0008-5472.CAN-06-1867 ID - Saccani2006 ER - TY - JOUR AU - Hagemann, T. AU - Biswas, S. K. AU - Lawrence, T. AU - Sica, A. AU - Lewis, C. E. PY - 2009 DA - 2009// TI - Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB JO - Blood VL - 113 UR - https://doi.org/10.1182/blood-2008-12-172825 DO - 10.1182/blood-2008-12-172825 ID - Hagemann2009 ER - TY - JOUR AU - Qian, B. Z. AU - Pollard, J. W. PY - 2010 DA - 2010// TI - Macrophage diversity enhances tumor progression and metastasis JO - Cell VL - 141 UR - https://doi.org/10.1016/j.cell.2010.03.014 DO - 10.1016/j.cell.2010.03.014 ID - Qian2010 ER - TY - JOUR AU - Powell, J. D. AU - Boodoo, S. AU - Horton, M. R. PY - 2004 DA - 2004// TI - Identification of the molecular mechanism by which TLR ligation and IFN-gamma synergize to induce MIG JO - Clin Dev Immunol VL - 11 UR - https://doi.org/10.1080/10446670410001670535 DO - 10.1080/10446670410001670535 ID - Powell2004 ER - TY - JOUR AU - Lin, Y. AU - Bai, L. AU - Chen, W. AU - Xu, S. PY - 2010 DA - 2010// TI - The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy JO - Expert Opin Ther Targets VL - 14 UR - https://doi.org/10.1517/14728220903431069 DO - 10.1517/14728220903431069 ID - Lin2010 ER -