TY - JOUR AU - Schneider, José AU - Gonzalez-Roces, Severino AU - Pollán, Marina AU - Lucas, Raul AU - Tejerina, Armando AU - Martin, Miguel AU - Alba, Alfonso PY - 2001 DA - 2001/06/01 TI - Expression of LRP and MDR1 in locally advanced breast cancer predicts axillary node invasion at the time of rescue mastectomy after induction chemotherapy JO - Breast Cancer Research SP - 183 VL - 3 IS - 3 AB - Axillary node status after induction chemotherapy for locally advanced breast cancer has been shown on multivariate analysis to be an independent predictor of relapse. However, it has been postulated that responders to induction chemotherapy with a clinically negative axilla could be spared the burden of lymphadenectomy, because most of them will not show histological nodal invasion. P-glycoprotein expression in the rescue mastectomy specimen has finally been identified as a significant predictor of patient survival. SN - 1465-542X UR - https://doi.org/10.1186/bcr293 DO - 10.1186/bcr293 ID - Schneider2001 ER -