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Figure 7 | Breast Cancer Research

Figure 7

From: Analysis of EpCAM positive cells isolated from sentinel lymph nodes of breast cancer patients identifies subpopulations of cells with distinct transcription profiles

Figure 7

EpCAM-IMS enriched cell populations are also enriched for EGFR, Wnt5B and SPARC RNA expression. RT-PCR analysis targeting EGFR, Wnt5B and SPARC all showed increased expression of these transcripts in EpCAM enriched cell populations compared with the corresponding EpCAM depleted cell populations (separated by IMS). This was true in SLN samples with hMAM expression (first eight samples; SLN 532 to 556) and in SLN samples negative for hMAM (last nine samples, SLN 530 to 554). Fold change was calculated relative to the average expression of each gene.

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Breast Cancer Research

ISSN: 1465-542X

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