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Table 6 Genotype distribution of four SNPs in FGFR2a

From: Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10

rs2981582 rs2981578 rs10736303 rs7895676 Number of patients
CT AG AG CT 29
TT GG GG CC 22
CC AA AA TT 21
CT GG GG CC 7
CC AG AG CT 5
TT AA AA TT 1
Total     85b
  1. aFGFR2: fibroblast growth factor receptor 2 gene. The number of patients who carry each combination of the four genotypes is shown in the right-hand column. Although we have no haplotype information, the genotype distribution shows the strong linkage disequilibrium present within this region. The alleles associated with increased breast cancer risk are rs2981582: T; rs2981578: G; rs10736303: G; and rs7895676: C. bFor the remaining13 patients, only rs2981578 was genotyped; of these patients, 5 carried AA, 5 carried AG and 3 carried GG.