Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10

Table 1 Characteristics of the patient cohort^a

Characteristics	Data
Total number of patients	98
BRCA1/2 mutation carriers, n (%)	10 (10%)
Diagnosis
Mean age at diagnosis^b, years (±SD)	55 (±14)
Invasive breast cancer, n	83
In situ breast cancer, n	8
Prophylactic surgery, no cancer, n	7
Tumor characteristics (n = 91)
ER status	54 positive, 20 negative, 17 unknown

^aSD: standard deviation; ER: estrogen receptor. ^bAge at diagnosis of breast cancer. The seven patients who underwent prophylactic surgery were excluded from this analysis.

ISSN: 1465-542X