The relationship between FGFR2 mRNA expression and the rs2981578 genotype in skin fibroblast and skin epithelial cell cultures. (A) A significant correlation between the rs2981578 genotype and FGFR2 mRNA expression level as measured by quantitative real-time PCR was present in the 68 skin fibroblast cultures (P = 0.02; one-way ANOVA). The expression levels were log2-transformed and normalized to HNRPM and TBP expression. (B) FGFR2 mRNA expression and rs2981578 genotypes in 25 skin epithelial cell cultures (P = 0.73; one-way ANOVA). The expression levels were log2-transformed and normalized to HNRPM, SRPR and TBP expression. Each dot represents the expression level in one patient.