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Figure 1 | Breast Cancer Research

Figure 1

From: Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10

Figure 1

The relationship between FGFR2 mRNA expression and the rs2981578 genotype in skin fibroblast and skin epithelial cell cultures. (A) A significant correlation between the rs2981578 genotype and FGFR2 mRNA expression level as measured by quantitative real-time PCR was present in the 68 skin fibroblast cultures (P = 0.02; one-way ANOVA). The expression levels were log2-transformed and normalized to HNRPM and TBP expression. (B) FGFR2 mRNA expression and rs2981578 genotypes in 25 skin epithelial cell cultures (P = 0.73; one-way ANOVA). The expression levels were log2-transformed and normalized to HNRPM, SRPR and TBP expression. Each dot represents the expression level in one patient.

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