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Table 3 Serum markers and CTC levels in metastatic breast cancer patients

From: Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer

CAIX/TIMP-1

n (100%)

CTC < 5 cells

CTC > = 5 cells

Total

245 (100%)

123 (100%)

122 (100%)

Both non-elevated

135 (55%)

83 (68%)

52 (43%)

TIMP-1 elevated

66 (27%)

21 (17%)

45 (37%)

CAIX elevated

88 (36%)

31 (25%)

57 (47%)

Both elevated

44 (18%)

12 (10%)

32 (26%)

  1. CAIX, carbonic anhydrase IX; CTC, circulating tumor cell; TIMP, tissue inhibitor of metalloproteinase.