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Table 3 Serum markers and CTC levels in metastatic breast cancer patients

From: Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer

CAIX/TIMP-1 n (100%) CTC < 5 cells CTC > = 5 cells
Total 245 (100%) 123 (100%) 122 (100%)
Both non-elevated 135 (55%) 83 (68%) 52 (43%)
TIMP-1 elevated 66 (27%) 21 (17%) 45 (37%)
CAIX elevated 88 (36%) 31 (25%) 57 (47%)
Both elevated 44 (18%) 12 (10%) 32 (26%)
  1. CAIX, carbonic anhydrase IX; CTC, circulating tumor cell; TIMP, tissue inhibitor of metalloproteinase.