Table 2 Mean survival in correlation to CTC positivity, TIMP-1 and CAIX levels

CTC

   < 5 cells

10.9 (9.4-12.5)

0.118

20.1 (18.8-21.5)

< 0.01

   ≥ 5 cells

9.3 (7.8-10.9)

14.0 (12.8-21.5)

TIMP-1

   Non elevated

11.4 (10.1-12.7)

< 0.01

19.1 (18.0-20.3)

< 0.01

   Elevated

7.2 (5.6-8.9)

11.5 (9.4-13.6)

CAIX

   Non elevated

11.7 (10.3-13.1)

< 0.01

19.1 (17.8-20.4)

< 0.01

   Elevated

7.5 (6.0-9.0)

13.4 (11.4-15.4)

TIMP-1/CAIX

   Both non-elevated

12.4 (10.9-13.9)

< 0.01

20.1 (18.8-21.3)

< 0.01

   Both elevated

7.0 (5.0-9.0)

11.1(8.5-13.6)