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Table 3 Incidence of Disease recurrence and deaths according to CTC detection and hormonal receptor status

From: Cytokeratin-19 mRNA-positive circulating tumor cells during follow-up of patients with operable breast cancer: prognostic relevance for late relapse

HR Status

CK-19 mRNA

No of patients

Relapses

 

Deaths

 
   

Yes

N (%)

No

N (%)

Fisher's Exact test, P

Dead

N (%)

Alive

N (%)

Fisher's Exact test, P

ER(-)/PR(-)

Persistently Positive

22

9 (40.1)

13(59.9)

P = 0.044

8 (34.4)

16 (63.6)

P = 0.009

 

Persistently Negative

24

3 (12.5)

21 (87.5)

 

1(4.1)

24 (95.9)

 

ER(+) and/or PR(+)

Persistently Positive

60

26 (43.3)

34 (46.7)

P < 0.001

15 (25)

45 (75)

P = 0.007

 

Persistently Negative

39

4 (10.2)

35 (89.2)

 

2 (5.1)

37 (94.9)

 
  1. CK-19, cytokeratine-19; HR, hormonal receptor; ER, estrogens receptor; PR, progesterone receptor.