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Table 2 Incidence of disease recurrence and deaths according to the detection of CK-19 mRNA-positive circulating tumor cells

From: Cytokeratin-19 mRNA-positive circulating tumor cells during follow-up of patients with operable breast cancer: prognostic relevance for late relapse

CK-19 mRNA No of patients Relapses   Deaths  
   Yes
N (%)
No
N (%)
Fisher's Exact test, P Dead
N (%)
Alive
N (%)
Fisher's Exact test, P
Persistently Positive 99 36 (36.4) 63 (63.6) P < 0.001 24 (24.2) 75 (75.8) P = 0.001
Persistently Negative 80 9 (11.2) 71 (88.8)   5(6.3) 75 (93.8)  
Positive Turn to negative 64 5 (7.8) 59 (92.2) P < 0.001
versus persistently positive
3 (4.7) 61 (95.3) P = 0.001
versus persistently positive
Negative Turn to positive 69 13 (18.8) 56 (81.2) P = 0.016
versus persistently positive
9 (13.0) 60 (87.0) P = 0.079
versus persistently positive
  1. While also,
  2. P = .248 for relapse of turn to positive versus persistently negative
  3. P = .172 for deaths of turn to positive versus persistently negative
  4. CK-19, cytokeratine-19.