Risk of reduced overall survival after a breast cancer diagnosis. Hazard ratios by octiles or extreme levels of plasma C-reactive protein (CRP) are based on 2,910 women from the Copenhagen Breast Cancer Study who were observed for up to seven years after a diagnosis of breast cancer. Model 1: adjusted for age at diagnosis. Model 2: adjusted for age at diagnosis, tumour size, lymph node status, presence of distant metastases, tumour grade, and estrogen receptor, progesterone receptor, and HER2 status. Model 3: adjusted for the above-mentioned covariates and smoking, alcohol consumption, body mass index, menopausal status, and cardiovascular disease.