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Figure 2 | Breast Cancer Research

Figure 2

From: NF-κB, stem cells and breast cancer: the links get stronger

Figure 2

Hypothetical model of the differentiation hierarchy within the mammary epithelium and potential relationships with breast cancer subtypes. NF-κB activation through the canonical or the non-canonical pathway is depicted as p50/p65 or p52/RelB heterodimers, respectively. Cell surface markers used for the isolation of human epithelial cell subsets are shown in blue. Adapted from [32, 33]. ER, oestrogen receptor; PR, progesterone receptor.

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