Table 2 Correlation analysis of intrinsic subtypes with clinicopathological parameters, Treg and CXCL12 expression (n = 456)
| Â | Luminal (n = 289) | HER2 (n = 75) | Basal-like (n = 62) | Negative (n = 30) | P-value |
|---|---|---|---|---|---|
Patient age | Â | Â | Â | Â | Â |
   Median (years) | 56.0 | 55.2 | 54.0 | 52.7 | 0.64 |
Tumour size | Â | Â | Â | Â | Â |
   Median | 18.0 | 22.0 | 22.5 | 20.5 | 0.40 |
Tumour grade | Â | Â | Â | Â | < 0.001 |
1 | 71 (25%) | 4 (5%) | 2 (3%) | 4 (13%) | Â |
2 | 156 (55%) | 16 (22%) | 12 (20%) | 12 (40%) | Â |
3 | 58 (20%) | 54 (73%) | 47 (77%) | 14 (47%) | Â |
Nodal status | Â | Â | Â | Â | 0.75 |
Negative | 162 (56%) | 40 (54%) | 34 (55%) | 17 (57%) | Â |
Positive | 125 (44%) | 34 (46%) | 28 (45%) | 13 (43%) | Â |
Treg | Â | Â | Â | Â | < 0.001 |
< 15 | 159 (62%) | 28 (39%) | 19 (25%) | 23 (92%) | Â |
≥15 | 99 (38%) | 43 (61%) | 36 (75%) | 2 (8%) |  |
median | 7.64 | 33.54 | 25.46 | 0.83 | Â |
CXCL12 | Â | Â | Â | Â | 0.050 |
Negative | 36 (26%) | 22 (47%) | 11 (41%) | 6 (35%) | Â |
Positive | 102 (74%) | 25 (53%) | 16 (59%) | 11 (65%) | Â |