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Table 2 PRL and PRLR single-nucleotide polymorphisms genotyped in the Polish Breast Cancer Study

From: Genetic variation in PRL and PRLR, and relationships with serum prolactin levels and breast cancer risk: results from a population-based case-control study in Poland

Single-nucleotide polymorphism Chromosome Base pair coordinatea Location Alleles MAFb P HWE c
PRLR       
   rs37364 5 35108137 Intron 7 A/C 0.21 0.58
   rs43215 5 35122726 Intron 3 G/A 0.12 0.67
   rs249537 5 35125057 Intron 3 C/T 0.11 3.0 × 10-3
   rs7734558 5 35150368 Intron 3 C/T 0.48 0.03
   rs62355518 5 35218778 Intron 3 A/G 0.16 0.68
   rs10941235 5 35221337 Intron 3 G/A 0.27 0.49
   rs13436213 5 35221583 Intron 3 G/A 0.35 1
   rs4425481 5 35221654 Intron 3 G/T 0.06 0.20
   rs1610218 5 35222451 Intron 3 G/A 0.04 0.63
   rs17249539 5 35233127 Intron 3 C/G 0.12 0.79
   rs12153280 5 35235019 Intron 3 G/T 0.11 <1.0 × 10-4
   rs873456 5 35235414 Intron 3 G/T 0.34 0.90
   rs7718468 5 35236793 Intron 3 T/C 0.32 0.53
   rs34024951 5 35246079 Intron 3 G/A 0.10 0.95
   rs9292575 5 35250262 Intron 3 C/A 0.09 0.74
   rs10038062 5 35256276 Intron 3 A/G 0.09 0.76
   rs7731880 5 35257203 Intron 3 G/C 0.12 <1.0 × 10-4
   rs931741 5 35257808 Intron 3 C/G 0.31 0.83
   rs7735260 5 35262772 Intron 3 C/T 0.16 4.9 × 10-3
   rs10068521 5 35266137 Exon 1 C/G 0.03 0.42
PRL       
   rs849872 6 22391011 3' UTR A/G 0.15 0.60
   rs849870 6 22391864 3' UTR G/A 0.14 0.56
   rs1205960 6 22396139 3' UTR G/A 0.25 0.13
   rs849886 6 22399346 Intron 3 G/A 0.46 0.94
   rs2244502 6 22402966 Intron 3 A/T 0.31 0.23
   rs12202764 6 22403312 Intron 3 A/T 0.27 0.16
   rs3756824 6 22406716 5' G/C 0.03 0.07
   rs9466314 6 22414284 5' T/T 0 1
  1. aSingle-Nucleotide Polymorphism database (dbSNP) build 36.3. bMinor allele frequency in controls only. cTest of Hardy-Weinberg equilibrium in controls only. PRL, prolactin (gene); PRLR, prolactin receptor (gene); UTR, untranslated region.