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Table 8 Relative risk of other second cancers* among patients given radiation therapy, by age-at- treatment

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Age-at-treatment RRaunadjusted for chemotherapy and hormonal therapy (95% CIb) RRaadjusted for chemotherapy and hormonal therapy (95% CIb) Cases/women with radiotherapy Cases/women with no radiotherapy
<50 1.54 (0.60, 3.93) 1.36 (0.53, 3.51) 9/584 (1.5%) 10/632 (1.6%)
50 to 64 2.44 (1.12, 5.30)** 2.36 (1.08, 5.14)** 18/549 (3.3%) 11/687 (1.6%)
65+ 0.92 (0.18, 4.66) 0.82 (0.16, 4.13) 2/134 (1.5%) 8/494 (1.6%)
  1. * Other second cancers are all second cancers other than contralateral breast cancer and leukaemia.
  2. ** P <0.05.
  3. a Relative risk is calculated based on a follow-up of five or more years.
  4. b Confidence interval.