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Table 6 Relative risk of all second cancers among patients given radiotherapy, by menopausal status

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Postmenopausala RRbunadjusted for chemotherapy and hormonal therapy (95% CIc) RRbadjusted for chemotherapy and hormonal therapy (95% CIc) Cases/women with radiotherapy Cases/women with no radiotherapy
Yes - natural 1.61 (1.13, 2.29)* 1.48 (1.04, 2.12)* 36/582 (6.2%) 49/1,072 (4.6%)
Yes - ovariectomy 1.40 (0.78, 2.45) 1.29 (0.73, 2.26) 4/63 (6.3%) 2/63 (3.2%)
No 0.90 (0.62, 1.32) 0.84 (0.58, 1.24) 33/621 (5.3%) 43/678 (6.3%)
  1. * P <0.05.
  2. a Menopausal status at the time of treatment.
  3. b Relative risk is calculated based on a follow-up of five or more years.
  4. c Confidence interval.