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Table 6 Relative risk of all second cancers among patients given radiotherapy, by menopausal status

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Postmenopausala

RRbunadjusted for chemotherapy and hormonal therapy (95% CIc)

RRbadjusted for chemotherapy and hormonal therapy (95% CIc)

Cases/women with radiotherapy

Cases/women with no radiotherapy

Yes - natural

1.61 (1.13, 2.29)*

1.48 (1.04, 2.12)*

36/582 (6.2%)

49/1,072 (4.6%)

Yes - ovariectomy

1.40 (0.78, 2.45)

1.29 (0.73, 2.26)

4/63 (6.3%)

2/63 (3.2%)

No

0.90 (0.62, 1.32)

0.84 (0.58, 1.24)

33/621 (5.3%)

43/678 (6.3%)

  1. * P <0.05.
  2. a Menopausal status at the time of treatment.
  3. b Relative risk is calculated based on a follow-up of five or more years.
  4. c Confidence interval.