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Table 3 Relative risk of all second cancers among patients given radiotherapy, by period of follow-up

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Follow-up period (years)

RRaunadjusted for chemotherapy and hormonal therapy (95% CIb)

RRaadjusted for chemotherapy and hormonal therapy (95% CIb)

Case/women with radiotherapy

Cases/women with no radiotherapy

2 to 4

0.52 (0.33, 0.82)*

0.44 (0.28, 0.70)*

37/2,339 (1.6%)

53/2,377 (2.2%)

5 to 9

1.20 (0.79, 1.82)

1.08 (0.71, 1.65)

43/1,267 (3.4%)

56/1,813 (3.1%)

10 to 14

1.40 (0.75, 2.64)

1.34 (0.71, 2.52)

16/390 (4.1%)

28/972 (2.9%)

15+

0.99 (0.41, 2.41)

1.13 (0.46, 2.77)

14/230 (6.0%)

10/307 (3.3%)

  1. * P <0.05.
  2. a Relative risk.
  3. b Confidence interval.