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Table 12 Relative risk of all second cancer due to combined therapy* compared with radiotherapy only

From: Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy

Age-at-treatment (years)

Relative risk (95% CIa)

P-value

Cases/women with RT plus chemotherapy or/and hormonal therapy

Cases/women with only RT

<50

0.43 (0.16, 1.14)

0.09

5/164 (3.0%)

27/420 (6.4%)

50 to 64

0.44 (0.15, 1.29)

0.14

4/142 (2.8%)

31/407 (7.6%)

65+

0.82 (0.09, 7.51)

>0.5

1/128 (0.8%)

5/106 (4.7%)

All

0.47 (0.23, 0.92)

0.03

10/334 (3.0%)

63/933 (6.7%)

  1. * Radiotherapy plus chemotherapy or/and hormonal therapy.
  2. a Confidence interval.