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Table 1 Combination indices for apoptosis induced by flutamide and CI-1040 treatments

From: Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer

 

Cell line

Treatment

HCC-1954

MDA-MB-453

HCC-202

CI-1040, μM

5

10

5

10

5

10

CI values FLU 20, μM

0.7

0.7

0.7

0.75

0.6

0.7

CI values FLU 30, μM

0.8

0.75

0.65

0.7

0.75

0.7

  1. CI: combination index, FLU: flutamide. CI-1040 and flutamide concentrations are shown in μM.
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Breast Cancer Research

ISSN: 1465-542X

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