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Table 1 Combination indices for apoptosis induced by flutamide and CI-1040 treatments

From: Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer

  Cell line
Treatment HCC-1954 MDA-MB-453 HCC-202
CI-1040, μM 5 10 5 10 5 10
CI values FLU 20, μM 0.7 0.7 0.7 0.75 0.6 0.7
CI values FLU 30, μM 0.8 0.75 0.65 0.7 0.75 0.7
  1. CI: combination index, FLU: flutamide. CI-1040 and flutamide concentrations are shown in μM.