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Table 4 Summary of EGFR mutations detected in primary tumours of triple negative breast cancers (n = 8)

From: Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy

Mutations Number of samples (%)
Exon 19  
del E746 to A750 (15 bp deletion) 2/70 (2.9%)
del S752 to I759 (24 bp deletion) 2/70 (2.9%)
inversion of complementary strand 1/70 (1.5%)
Exon 21  
L858R 1/70 (1.5%)
T847I 2/70 (2.9%)
Total 8/70 (11.4%)
Single nucleotide polymorphisms  
Exon 18  
T725T 3/70 (4.3%)
Exon 20  
Q787Q 6/70 (8.6%)