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Table 4 Summary of EGFR mutations detected in primary tumours of triple negative breast cancers (n = 8)

From: Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy

Mutations

Number of samples (%)

Exon 19

 

del E746 to A750 (15 bp deletion)

2/70 (2.9%)

del S752 to I759 (24 bp deletion)

2/70 (2.9%)

inversion of complementary strand

1/70 (1.5%)

Exon 21

 

L858R

1/70 (1.5%)

T847I

2/70 (2.9%)

Total

8/70 (11.4%)

Single nucleotide polymorphisms

 

Exon 18

 

T725T

3/70 (4.3%)

Exon 20

 

Q787Q

6/70 (8.6%)