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Table 1 Correlation of Pokemon expression with clinicopathological parametersa

From: Pro-oncogene Pokemon promotes breast cancer progression by upregulating survivin expression

  Pokemon(n= 182)  
Variables 3 2 1 0 Pvalue
Subtotal, n (%) 72 (39.6) 69 (37.9) 17 (9.3) 24 (13.2)  
Age, yr (%)      0.2451
   >50 58 (40.8) 55 (38.7) 13 (9.2) 16 (11.3)  
   ≤50 13 (33.3) 14 (35.9) 4 (10.3) 8 (20.5)  
Tumor types, n (%)      0.8733
   Colloid 3 (37.5) 3 (37.5) 1 (12.5) 1 (12.5)  
   Ductal 35 (47.9) 26 (35.6) 5 (6.8) 7 (9.6)  
   Lobular 14 (53.8) 8 (30.8) 3 (11.5) 1 (3.8)  
Tumor size, cm3 (%)      0.0148
   >2 47 (42.7) 46 (41.8) 9 (8.2) 8 (7.3)  
   ≤2 23 (33.8) 22 (32.3) 8 (11.8) 15 (22.1)  
Node metastasis, n (%)      0.0014
   Positive 49 (44.1) 38 (34.2) 8 (7.2) 16 (14.4)  
   Negative 22 (31.9) 30 (43.5) 9 (13.0) 8 (11.6)  
Nuclear grade, n (%)      0.057
   1 5 (23.8) 9 (42.6) 2 (9.5) 5 (23.8)  
   2 40 (40.4) 38 (38.4) 12 (12.1) 9 (9.1)  
   3 25 (45.5) 20 (38.4) 3 (12.1) 7 (9.1)  
ER, n (%)      0.429
   Positive 38 (37.6) 39 (38.6) 11 (10.9) 13 (12.9)  
   Negative 34 (42.0) 30 (37.0) 6 (7.4) 11 (13.6)  
PR, n (%)      0.3444
   Positive 41 (40.2) 34 (33.3) 14 (13.7) 13 (12.8)  
   Negative 31 (38.8) 35 (43.8) 3 (3.7) 11 (14.7)  
HER2, n (%)      0.2309
   Positive 31 (38.7) 28 (35.0) 7 (8.8) 14 (17.5)  
   Negative 41 (38.3) 41 (38.3) 11 (10.3) 14 (13.1)  
  1. aData are from the Yale Tissue Microarray-23, in which 182 breast cancer cases were histologically interpretable and analyzed for the correlation of Pokemon expression with clinicopathological parameters. ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.