Figure 1
From: Pro-oncogene Pokemon promotes breast cancer progression by upregulating survivin expression
Pokemon expression in breast cancer tissues and its relationship with patient survival. (A) Immunohistochemistry indicating Pokemon expression in normal and malignant breast tissues. Results were scored by a researcher blinded to the samples and by a pathologist. The images show Pokemon expression in (a) normal breast lobules and in breast cancers scored as (b) 1, (c) 2 and (d) 3, respectively. (B) Kaplan-Meier plots of (i) overall survival (n = 175, P = 0.01) and (ii) disease-related survival (n = 79, P = 0.0134). Data are from the Yale Tissue Microarray (YTMA)-23 microarray containing 175 breast cancer cases with clinical data and more than 30 years of follow-up. In disease-related survival plots, disease-free survival or patients who died as a result of breast cancer are included.