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Table 4 Correlation of sera autoantibodies to MUC1 glycopeptide combinational subset with clinical variables

From: Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis

  

Autoantibody positive

 

Strong autoantibody positiveA

 

NB

% positive

NA,B

% positive

Age at diagnosis

 

P = 0.001 C

 

P < 0.001

<50

63

5

61

2

50 to 59

132

14

125

9

60 to 69

136

27

129

23

70+

64

27

57

18

Stage

 

P = 0.215

 

P = 0.104

Node negative

200

22

189

17

Node positive

193

17

181

11

Positive nodes

 

P = 0.195

 

P = 0.219

0

200

22

189

17

1 to 3

124

19

114

12

4+

69

12

67

9

Clin tumour size

 

P = 0.483

 

P = 0.306

0 to 2 cm

133

19

129

16

2.1 to 4 cm

176

20

162

13

>4 cm

74

14

70

9

Tumour grade/type

 

P = 0.165

 

P = 0.016

ID Grade I

37

30

35

26

ID Grade II + I Lob

195

19

187

15

ID Grade III

120

16

109

7

ER Status

 

P = 0.883

 

P = 0.183

ER negative

131

18

120

11

ER positive

211

19

204

16

Parity

 

P = 0.730

 

P = 0.436

0 children

87

23

82

18

1 to 2 children

171

19

164

16

3+ children

96

19

88

11

Metastases to 15 yrs

 

P = 0.058

 

P = 0.028

No

238

22

237

17

Yes

155

14

133

9

  1. A Weak positives excluded
  2. B Total number in that group for the variable.
  3. C Using Chi-squared test for equality of distributionsBold text indicates a significant correlation.