Table 1 The differences between TM10 and TM2H cell lines in the cell cycle profile and protein status
From: Mechanisms of suberoylanilide hydroxamic acid inhibition of mammary cell growth
| Â | TM10 cell line | TM2H cell line |
|---|---|---|
| Â | (p53 wt) | (p53 null) |
Nuclear proteins | Â | Â |
   E2F-1 | 1 | 4.8 |
   PCNA | 1 | 4.0 |
   Rb2/p130 | 1 (predominantly | 1 (predominantly |
| Â | hypophosphorylation) | hypophosphorylation) |
   p21/Cip1 | Strongly detectable | Weakly detectable |
Cyclin-dependent kinase activity | Â | Â |
   D1 | 1 | 2.2 |
   E | 1 | 1.7 |
   A | 1 | 3 |
   BrdU index | 16% | 34% |
Cell cycle profile | Â | Â |
   G0/G1 | 57% | 39% |
   S | 18% | 28% |