From: Expression of microRNA and their gene targets are dysregulated in preinvasive breast cancer
microRNA expression | Gene expression | miRNA:mRNA | ||||
---|---|---|---|---|---|---|
miRNA | Fold change | Probe ID | Gene symbols, gene names | Fold change | Expression correlation | P valueb |
let-7c | 0.03 | 203481_at | C10ORF6, chromosome 10 open reading frame 6 | 1.58 | -0.58 | 1.88E-02 |
 |  | 218567_x_at | DPP3, dipeptidylpeptidase 3 | 2.31 | -0.49 | 5.4E-02 |
 |  | 203358_s_at | EZH2, enhancer of zeste homolog 2 (Drosophila) | 2.36 | -0.64 | 7.69E-03 |
 |  | 209283_at | SLC20A1, solute carrier family 20 (phosphate transporter), member 1 | 2.06 | -0.30 | 2.53E-01 |
 |  | 203358_s_at | TRIB1, tribbles homolog 1 (Drosophila) | 1.77 | -0.48 | 5.84E-02 |
miR-10b | 0.04 | 202357_s_at | SDC1, syndecan 1 | 2.06 | -0.28 | 2.96E-01 |
miR-125b | 0.05 | 203744_at | HMGB3, high-mobility group box 3 | 2.13 | -0.61 | 1.27E-02 |
 |  | 209613_s_at | NRIP1, nuclear receptor interacting protein 1 | 2.25 | -0.39 | 1.36E-01 |
 |  | 213004_at | MEMO1, mediator of cell motility 1 | 1.73 | -0.59 | 1.54E-02 |
miR-17-3p | 0.12 | 203744_at | HMGB3, high-mobility group box 3 | 2.13 | -0.49 | 5.66E-02 |
 |  | 212446_s_at | LASS6, LAG1 longevity assurance homolog 6 | 1.78 | -0.31 | 2.38E-01 |
 |  | 211653_x_at | MAP7, microtubule-associated protein 7 | 1.73 | -0.49 | 5.19E-02 |
 |  | 213492_at | SERP1, stress-associated endoplasmic reticulum protein 1 | 1.80 | -0.23 | 3.84E-01 |
 |  | 203213_at | SAR1B, SAR1 gene homolog B (Saccharomyces cerevisiae) | 1.95 | -0.07 | 8.03E-01 |
 |  | 202381_at | ADAM9, ADAM metallopeptidase domain 9 | 2.04 | -0.45 | 7.89E-02 |
miR-181b | 5.46 | 221234_s_at | BACH2, BTB and CNC homology 1 basic leucine zipper transcription factor 2 | 0.47 | -0.30 | 2.62E-01 |
 |  | 212914_at | CBX7, chromobox homolog 7 | 0.44 | -0.30 | 2.67E-01 |
 |  | 204753_s_at 204755_x_at 204754_at | HLF, hepatic leukemia factor | 0.24 0.28 0.31 | -0.19 -0.52 -0.45 | 4.84E-01 3.82E-02 7.70E-02 |
 |  | 204567_s_at | NMT2, N-myristoyltransferase 2 | 0.58 | -0.35 | 1.81E-01 |
 |  | 202274_at 200974_at | NR3C1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.46 0.57 | -0.44 -0.57 | 8.86E-02 2.21E-02 |
miR-182 | 72.35 | 221234_s_at | BACH2, BTB and CNC homology 1 basic leucine zipper transcription factor 2 | 0.47 | -0.73 | 1.41E-03 |
 |  | 210347_s_at 219497_s_at 219498_s_at | BCL11A, B-cell CLL/lymphoma 11A | 0.27 0.42 0.43 | -0.65 -0.69 -0.80 | 6.31E-03 2.86E-03 2.19E-04 |
 |  | 221530_s_at | BHLHB3, basic helix-loop-helix domain containing, class B, 3 | 0.47 | -0.55 | 2.71E-02 |
 |  | 204851_s_at 204850_s_at | DCX, doublecortex; lissencephaly, X-linked (doublecortin) | 0.13 0.30 | -0.83 -0.67 | 7.48E-05 4.63E-03 |
 |  | 209691_s_at | DOK4, docking protein 4 | 0.56 | -0.53 | 3.65E-02 |
 |  | 209905_at 214651_s_at | HOXA9, homeobox A9 | 0.10 0.31 | -0.64 -0.55 | 8.18E-03 2.63E-02 |
 |  | 64900_at | LPHN2, latrophilin 2 | 0.37 | -0.62 | 9.87E-03 |
 |  | 219497_s_at | PRKD1, protein kinase D1 | 0.54 | -0.59 | 1.61E-02 |
 |  | 210735_s_at | RIMS3, regulating synaptic membrane exocytosis 3 | 0.52 | -0.73 | 1.25E-03 |
 |  | 205022_s_at | FOXN3, checkpoint repressor 1 | 0.50 | -0.67 | 4.40E-03 |
 |  | 221935_s_at | NCAM1, neural cell adhesion molecule 1 | 0.43 | -0.41 | 1.19E-01 |
 |  | 212914_at | CBX7, chromobox homolog 7 | 0.44 | -0.57 | 2.22E-02 |
 |  | 204567_s_at | NMT2, N-myristoyltransferase 2 | 0.58 | -0.26 | 3.26E-01 |
miR-183 | 51.88 | 221234_s_at | BACH2, BTB and CNC homology 1 basic leucine zipper transcription factor 2 | 0.47 | -0.75 | 7.83E-04 |
 |  | 204851_s_at 204850_s_at | DCX, doublecortex; lissencephaly, X-linked (doublecortin) | 0.13 0.30 | -0.82 -0.80 | 1.06E-04 2.16E-04 |
 |  | 201693_s_at | EGR1, early growth response 1 | 0.45 | -0.61 | 1.12E-02 |
 |  | 202274_at 200974_at | NR3C1, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.46 0.57 | -0.70 -0.45 | 2.77E-03 8.08E-02 |
miR-195 | 0.13 | 217852_s_at | ARL8B, ADP ribosylation factor-like 8B | 1.64 | -0.31 | 2.49E-01 |
 |  | 208712_at | CCND1, cyclin D1[43] | 2.30 | -0.33 | 2.19E-01 |
 |  | 208653_s_at | CD164, CD164 molecule, sialomucin | 2.40 | -0.54 | 3.16E-02 |
 |  | 202596_at | ENSA, endosulfine α | 2.03 | -0.37 | 1.54E-01 |
 |  | 211653_x_at | MAP7, microtubule-associated protein 7 | 1.73 | -0.52 | 4.00E-02 |
 |  | 221935_s_at | RAD23B, RAD23 homolog B | 1.79 | -0.08 | 7.61E-01 |
 |  | 201341_at | TMEM33, transmembrane protein 33 | 1.62 | -0.30 | 2.64E-01 |
 |  | 212464_s_at 216442_x_at | WWP1, WW domain containing E3 ubiquitin protein ligase 1 | 2.79 2.83 | -0.49 -0.25 | 5.57E-02 5.57E-02 |
miR-204 | 0.08 | 217852_s_at | ARL8B, ADP-ribosylation factor-like 8B | 1.64 | -0.27 | 3.06E-01 |
 |  | 213492_at | SERP1, stress-associated endoplasmic reticulum protein 1 | 1.80 | -0.57 | 2.22E-02 |
miR-21 | 20.92 | 218992_at 219060_at | NFIB, nuclear factor I/B[42] | 0.43 0.52 | -0.75 -0.69 | 9.15E-04 3.28E-03 |
miR-7 | 5.19 | 213492_at | COL2A1, collagen type II, α1 | 0.51 | -0.12 | 6.61E-01 |
 |  | 204359_at | FLRT2, fibronectin leucine-rich transmembrane protein 2 | 0.35 | -0.49 | 5.36E-02 |
 |  | 206765_at | KCNJ2, potassium inwardly rectifying channel, subfamily J, member 2 | 0.33 | -0.73 | 1.35E-03 |
 |  | 214112_s_at | SNCA, synuclein α | 0.48 | -0.54 | 3.00E-02 |
 |  | 205022_s_at | FOXN3, checkpoint repressor 1 | 0.50 | -0.61 | 1.22E-02 |
miR-93 | 160.47 | 210347_s_at 219497_s_at 219498_s_at | BCL11A, B-cell CLL/lymphoma 11A | 0.27 0.42 0.43 | -0.75 -0.72 -0.71 | 7.40E-04 1.51E-03 2.11E-03 |
 |  | 204753_s_at 204755_x_at 204754_at | HLF, hepatic leukemia factor | 0.24 0.28 0.31 | -0.68 -0.81 -0.81 | 3.60E-03 1.44E-04 1.49E-04 |
 |  | 218992_at 219060_at | NFIB, nuclear factor I/B | 0.43 0.52 | -0.74 -0.65 | 1.14E-03 6.30E-03 |
 |  | 203963_at | RGL1, ral guanine nucleotide dissociation stimulator-like 1 | 0.53 | -0.58 | 1.79E-02 |
 |  | 204422_s_at 205117_at | TXNIP, thioredoxin-interacting protein | 0.36 0.49 | -0.69 -0.57 | 2.96E-03 2.14E-02 |