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Figure 5 | Breast Cancer Research

Figure 5

From: Interpreting breast international group (BIG) 1-98: a randomized, double-blind, phase III trial comparing letrozole and tamoxifen as adjuvant endocrine therapy for postmenopausal women with hormone receptor-positive, early breast cancer

Figure 5

STEPP analysis of 5-year disease-free survival (DFS) according to level of centrally assessed tumor markers. (a) Estrogen receptor (ER) status, (b) progesterone receptor (PgR) status, (c) Ki-67 labeling index status, and (d) HER2 status for 5,177 assessable patients enrolled in the four-arm option at a median follow up of 71 months. Rug plots along the x-axis display the distribution of individual values. Let, letrozole; STEPP, Subpopulation Treatment Effect Pattern Plot; Tam, tamoxifen. Reprinted with permission from Annals of Oncology [23]. Copyright 2011, Oxford University Press.

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