Figure 3From: Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individualsFamily 110 pedigree. Family pedigree of the index individual with the identified CHEK2 c.470T > C, c.792 + 39C > T, c.1100delC, and RAD50 c. 2398-32A > G variants. Individuals with breast cancer with age at diagnosis are marked with black circles. Other cancers are marked in grey and accompanied by age at diagnosis, if known. Index individual is marked with an arrow. Deceased individuals are indicated with a slash. Current ages of healthy females are marked if known. Br, breast cancer; Ca, cancer with unknown primary site; Pr, prostate.Back to article page