Figure 1From: Screening for BRCA1, BRCA2, CHEK2, PALB2, BRIP1, RAD50, and CDH1 mutations in high-risk Finnish BRCA1/2-founder mutation-negative breast and/or ovarian cancer individualsFamily 249 pedigree. Family pedigree of the index individual with the identified BRCA1 c.5095C > T variant (same variant was also identified in the daughter of the index individual and in the daughter of the index individual's paternal uncle). Individuals with breast or ovarian cancer with age at diagnosis are marked with black circles. Other cancers are marked in grey and accompanied by age at diagnosis, if known. Index individual is marked with an arrow. Deceased individuals are indicated with a slash. Current ages of healthy females are marked if known. Br, breast cancer; Co, colon; Kid, kidney; Mel, melanoma; Ov, ovarian cancer; To, tongue; Ute, uterus.Back to article page