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Table 4 Multivariate analysis using the Cox regression model of relapse-free survival in all breast cancers of validation cohort (N = 245)a

From: The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression

Characteristic

P value

Hazard ratio

95% CI for hazard ratios

SIAH2

0.47

1.24

0.7 to 2.2

Grade

   

   1 (reference)

0.54

  

   2

0.70

0.83

0.3 to 2.1

   3

0.70

1.22

0.4 to 3.3

Tumor size

0.12

1.37

0.9 to 2.2

Lymph node status

0.001

2.25

1.4 to 3.7

Tumor type

   

   Luminal

0.004

  

   Basal-like

0.005

3.0

1.4 to 6.4

   HER2

0.001

2.9

1.6 to 5.7

   Null

0.016

2.5

1.2 to 5.1

  1. aSIAH2, seven in absentiahomolog 2 gene.
  2. 95% CI, 95% confidence interval, HER2, human epidermal growth factor receptor 2.