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Figure 5 | Breast Cancer Research

Figure 5

From: During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein

Figure 5

ERBB2 and ERBB3 mRNA levels following depletion of apo-ER or apo-RARα1 in MCF-7 cells. Cells were treated with vehicle, E2 (1 nM) or transfected with control siRNA, ER siRNA or RARα siRNA. Ninety-six days later the cells were harvested to extract total RNA for the measurement of ERBB2 and ERBB3 by real time RT-PCR. Values are normalized to the GAPDH values. P-values for the differences noted in the text were ≤0.001.

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