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Figure 4 | Breast Cancer Research

Figure 4

From: Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice

Figure 4

In vivo prophylactic vaccination with anti-Id scFv protects against spontaneous mammary tumor development in MMTV.f.huHER2(Fo5) transgenic mice. The Kaplan-Meier disease-free survival plots illustrate the age of appearance of mammary tumors in (A) virgin females vaccinated with PBS (negative control), anti-HER2 trastuzumab, scFv69 or HER2-Fc and (B) primiparous females vaccinated with PBS (negative control), anti-Id scFv40 or scFv69, and HER2-Fc.

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Breast Cancer Research

ISSN: 1465-542X

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