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Table 4 Association analysis of rs7761846 within ESR1 under a dominant model in ER-positive case analysis

From: Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer

Sample

Control

Case

OR (95% CI)

Pvalue

Swedish

1,442

675

1.43 (1.10, 1.86)

0.007

Finnish

1,246

1669

1.10 (0.81, 1.48)

0.55

Combineda

2,688

2344

1.28 (1.05, 1.56)

0.014

  1. ER, estrogen receptor; OR, odds ratio; CI, confidence interval. aCombined analysis was performed on logistic regression adjusted by age and study.
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Breast Cancer Research

ISSN: 1465-542X

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