From: Rare, evolutionarily unlikely missense substitutions in CHEK2contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study
Center
Patients, n(%)
Controls, n(%)
Breast CFR Australia
5 (0.8%)
11 (2.1%)
Breast CFR Canada
1 (0.3%)
2 (0.4%)
Breast CFR Northern California
4 (1.0%)
1 (0.7%)
Total
10 (0.8%)
14 (1.2%)