α-TEA, doxorubicin and cisplatin induce apoptosis of p53 mutant, triple-negative human breast cancer cells. MDA-MB-231 and BT-20 breast cancer cells were treated with different concentrations of doxorubicin (DOXO) or cisplatin (CDDP) alone or in combination with α-TEA for 24 hours. Fluorescence-activated cell sorter/annexin V assays were used to determine the percentage of apoptotic cells (a), (b), (c), (d). Data expressed as mean ± standard deviation from three independent experiments. *P <0.05, significantly different from control. **P <0.05, significantly different from single treatments.