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Table 1 Association of FBXW7/hCDC4-β promoter methylation in 161 primary breast cancer patients with clinicopathological features

From: Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer

 

UM

(%)

M

(%)

P

Age

     

≤67

37

(45.1)

45

(54.9)

0.27

>67

43

(54.4)

36

(45.6)

 

ER

     

Negative

17

(37.7)

28

(62.3)

0.08

Positive

61

(54)

52

(46)

 

Unknown

2

 

1

  

PR

     

Negative

17

(40)

25

(60)

0.21

Positive

61

(52.5)

55

(47.5)

 

Unknown

2

 

1

  

LN

     

Negative

41

(50.6)

40

(49.4)

0.75

Positive

36

(47)

40

(53)

 

Unknown

3

 

1

  

Grade

     

I/II

64

(55.1)

52

(44.9)

0.017

III

13

(32.5)

27

(67.5)

 

Unknown

3

 

2

  

Stage

     

I/II

58

(52.2)

53

(47.8)

0.18

III

9

(36)

16

(64)

 

Unknown

12

 

12

  
  1. * Fisher's exact test. UM, unmethylated; M, methylated; ER, estrogen receptor; PR, progesterone receptor; LN, lymph node.
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Breast Cancer Research

ISSN: 1465-542X

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